PCB-twenty eight entered adipocytes faster versus other several congeners probably due to the faster unit weight, dimensions, and you may lipophilicity, if you are PCBs ?153 and you can ?118 remained involved in the lipophilic cell membrane layer and you can diffused alot more slow into the intracellular, hydrophobic cytoplasm of your own adipocyte (54)
This new dynamics off contaminant buildup in and release from In the would depend on the physic-chemicals attributes. The new partition coefficient has proven as a primary parameter governing the new consumption off lipophilic toxicants toward adipocytes. But not, also contained in this an excellent toxicant group, structural determinants determine physico-agents services that influence At the accumulation. Such as for example, some other PCB congeners can display distinct consumption and you will stores character towards adipocytes (54) (250) (249). You to definitely study compared this new buildup potential in the During the off about three PCB congeners: PCB ?twenty eight, ?153, and ?118 according to each one of the congeners physico-agents enjoys. Continue Reading Physico-chemicals functions and you can lipids dictate On Pop bioaccumulation